Journal of Research in Pharmacy Practice

Drug‑related problems among medical ward patients in Jimma university specialized hospital, Southwest Ethiopia

. Bereket Molla Tigabu; . Daniel Daba; . Belete Habte

Volume 3, Issue 1 , January 2014, Pages 1-5

Abstract

Objective: The increasing number of available drugs and drug users, as well as more complex drug regimens led to more side effects and drug interactions and complicates follow‑up. ... Read More Objective: The increasing number of available drugs and drug users, as well as more complex drug regimens led to more side effects and drug interactions and complicates follow‑up. The objective of this study was to assess drug‑related problems (DRPs) and associated factors in hospitalized patients.Methods: A hospital‑based cross‑sectional study design was employed. The study was conducted in Jimma University Specialized Hospital, Jimma, located in the south west of Addis Ababa. All patients who were admitted to the medical ward from February 2011 to March 2011 were included in the study. Data on sociodemographic variables, past medical history, drug history, current diagnosis, current medications, vital signs, and relevant laboratory data were collected using semi‑structured questionnaire and data collection forms which were filling through patient interview and card review. Data were analyzed using SPSS version 16 for windows. Descriptive statistics, cross‑tabs, Chi‑square, and logistic regression were utilized.Findings: Out of 257 study participants, 189 (73.5%) had DRPs and a total of 316 DRPs were identified. From the six classes of DRPs studied, 103 (32.6%) cases related to untreated indication or need additional drug therapy, and 49 (15.5%) cases related to high medication dosage. Unnecessary drug therapy in 49 (15.5%) cases, low medication dosage in 44 (13.9%) cases, and ineffective drug therapy in 42 (13.3%) cases were the other classes of problems identified. Noncompliance in 31 (9.8%) cases was the least prevalent DRP. Independent factors which predicted the occurrence of DRPs in the study population were sex, age, polypharmacy, and clinically significant potential drug‑drug interactions. The prevalence of DRPs was substantially high (73.5%).Conclusion: Drug‑related problems are common among medical ward patients. Indication‑related problems, untreated indication and unnecessary drug therapy were the most common types of DRPs among patients of our medical ward.

Antimicrobial susceptibility pattern of extended‑spectrum β‑lactamase‑producing bacteria causing nosocomial urinary tract infections in an Iranian referral teaching hospital

. Rasool Soltani; . Mohsen Ehsanpoor; . Farzin Khorvash; . Dariush Shokri

Volume 3, Issue 1 , January 2014, Pages 6-11

Abstract

Objective: Gram‑negative bacilli are the most important cause of nosocomial urinary tract infections (UTIs). The production of extended‑spectrum β‑lactamase (ESBL) enzymes is ... Read More

A comparative study of pre- and post‑menopausal breast cancer: Risk factors, presentation, characteristics and management

. Aruna Surakasula; . Govardhana Chary Nagarjunapu; . K. V. Raghavaiah

Volume 3, Issue 1 , January 2014, Pages 12-18

Abstract

Objective: Breast cancer is the most common female cancer worldwide and is the second most commonly diagnosed cancer in Indian women. This study evaluates the differences between ... Read More

Stability of antibacterial activity of Chlorhexidine and Doxycycline in bovine root dentine

. Abbas Ali Khademi; . Marjan Saleh; . Masoud Khabiri; . Sanaz Jahadi

Volume 3, Issue 1 , January 2014, Pages 19-22

Abstract

Objective: The aim of this study was to compare the substantivity of chlorhexidine (CHX) and doxycycline bond to the dentin in diffusion disk method.Methods: A total of 92 dentin ... Read More

Self‑medication among undergraduate medical students in Kuwait with reference to the role of the pharmacist

. Maryam Al-Hussaini; . Seham Mustafa; . Seham Ali

Volume 3, Issue 1 , January 2014, Pages 23-27

Abstract

Objective: The practice of self‑medication is growing world‑wide. It is associated with problems that may lead to potentially life‑threatening complications represent a priority to ... Read More Objective: The practice of self‑medication is growing world‑wide. It is associated with problems that may lead to potentially life‑threatening complications represent a priority to be investigated. The aim of this study was to estimate the prevalence of self‑medication among undergraduate medical students and to evaluate the possible role of the pharmacist in self‑medication in Kuwait.Methods: A descriptive cross‑sectional study was performed, using the questionnaire on a sample of 900 male and female students randomly selected from three health faculties in Kuwait. The prevalence of self‑medication, as well as the contribution of pharmacist in self‑medication was assessed. In addition, the role of the pharmacist as drug consultant for the students after getting the medication was evaluated.Findings: The overall prevalence of self‑medication was 97.8%. The age was significantly inversely proportional to self‑medication. There was a significant difference between male and female students in self‑medication practice. Headache was the highest health conditions that most frequently motivated self‑medication with 90.1% prevalence, followed by 84.7% for dysmenorrhea and 60.3% for constipation. Contribution of the pharmacist as a part of self‑medication care was low totally, with the highest rate for cough conditions 40.1%. However, the role of the pharmacist as a drug consultant was more noticeable after obtaining the drug, not before. Around 80.1% of the students request information from the pharmacist about doses, duration of treatments and side‑effects.Conclusion: The prevalence of self‑medication among undergraduate students in Kuwait is high and there were significant differences for age and gender. The contribution of the pharmacist was low in self‑medication, while it was high after getting the drugs for obtaining drug related information. The practice of self‑medication is alarming. Improved awareness about the role of pharmacist as a drug consultant for careful and cautious use of medicines available for self‑medication would be strongly recommended.

Evaluation of in vivo effects of Oxytocin on coagulation of parturient during cesarean delivery by thromboelastography

. Mohammad Golparvar; . Mehdi Esterabi; . Reihanak Talakoub; . Hamid Hajigholam Saryazdi

Volume 3, Issue 1 , January 2014, Pages 28-33

Abstract

Objective: Oxytocin routinely used as an uterotonic drug in cesarean delivery. Clothing problems, adverse effects on fibrinogen and bleeding were presented as side effects of oxytocin. ... Read More

A prospective study to compare the clinical efficacy of Tolvaptan with 3% hypertonic saline solution in hospitalized patients having hyponatremia

. Jobin Kunjumon Vilapurathu; . S. Rajarajan

Volume 3, Issue 1 , January 2014, Pages 34-36

Abstract

Objective: Hyponatremia is one of the most common electrolyte abnormalities in hospitalized patients. The treatment of hyponatremia is controversial as rapid correction of ... Read More

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Volume & Issue: Volume 3, Issue 1, January 2014

Drug‑related problems among medical ward patients in Jimma university specialized hospital, Southwest Ethiopia

Abstract

Antimicrobial susceptibility pattern of extended‑spectrum β‑lactamase‑producing bacteria causing nosocomial urinary tract infections in an Iranian referral teaching hospital

Abstract

A comparative study of pre- and post‑menopausal breast cancer: Risk factors, presentation, characteristics and management

Abstract

Stability of antibacterial activity of Chlorhexidine and Doxycycline in bovine root dentine

Abstract

Self‑medication among undergraduate medical students in Kuwait with reference to the role of the pharmacist

Abstract

Evaluation of in vivo effects of Oxytocin on coagulation of parturient during cesarean delivery by thromboelastography

Abstract

A prospective study to compare the clinical efficacy of Tolvaptan with 3% hypertonic saline solution in hospitalized patients having hyponatremia

Abstract