Journal of Research in Pharmacy Practice

Objective: The objective was to quantify the specialists’ prescription pattern in Iran and to point out the prescribing behavioral differences among several specialties.Methods: ... Read More

Identification and management of adverse effects of antipsychotics in a tertiary care teaching hospital

. Jisha Myalil Lucca; . Ramesh Madhan; . Gurumurthy Parthasarathi; . Dushad Ram

Volume 3, Issue 2 , April 2014, Pages 46-50

Abstract

Objective: Antipsychotics have revolutionized psychiatry by allowing significant numbers of patients in long‑term hospital settings to be discharged and successfully maintained ... Read More

Education alone is not enough in ventilator associated pneumonia care bundle compliance

. Hadi Hamishehkar; . Mahdi Vahidinezhad; . Simin Ozar Mashayekhi; . Parina Asgharian; . Hadi Hassankhani; . Ata Mahmoodpoor

Volume 3, Issue 2 , April 2014, Pages 51-55

Abstract

Objective: Ventilator‑associated pneumonia (VAP) described as a secondary and preventable consequence in mechanically ventilated patients, emerges 48 h or more after patients intubation. ... Read More

Assessing health conditions and medication use among the homeless community in Long Beach, California

. Mok Thoong Chong; . Jason Yamaki; . Megan Harwood; . Richard d’Assalenaux; . Ettie Rosenberg; . Okezie Aruoma; . Anupam Bishayee

Volume 3, Issue 2 , April 2014, Pages 56-61

Abstract

Objective: Persons experiencing homelessness are a vulnerable population and are at increased risk for morbidity and all‑cause mortality compared to the general population. This ... Read More

Adherence to American society of health‑system pharmacists surgical antibiotic prophylaxis guidelines in a teaching hospital

. Mohammadreza Rafati; . Afshin Shiva; . Amirhosein Ahmadi; . Omran Habibi

Volume 3, Issue 2 , April 2014, Pages 62-66

Abstract

Objective: Surgical site infections are the second most common type of adverse events occurring in hospitalized patients, whereas an estimated 40-60% of these infections are thought to ... Read More Objective: Surgical site infections are the second most common type of adverse events occurring in hospitalized patients, whereas an estimated 40-60% of these infections are thought to be preventable. Choice of regimen, administration timing or duration of antibiotic prophylaxis is reported to be inappropriate in approximately 25-50% of cases. We tried to evaluate an antibiotic administration pattern for surgical antibiotic prophylaxis in a teaching hospital.Methods: This study was conducted at the general surgery and orthopedic wards of a teaching hospital affiliated with Mazandaran University of Medical Sciences. The medical records of admitted patients who underwent different surgical procedures were reviewed. Compliance was assessed with the recommendations of the American Society of Health‑System Pharmacists’ guidelines for every aspect of antibiotic prophylaxis. All data were coded and analyzed by SPSS16 software using Student’s t‑test and Chi‑square test.Findings: During 1 year, 759 patients who underwent different surgeries were included in the study. Mean age of patients was 32.02 ± 18.79 years. Hand and foot fractures repair were the most frequent surgery types. About 56.4% of administered prophylactic antibiotics were in accordance with the American Society of Health System Pharmacists (ASHP) guidelines regarding prophylaxis indication. The most commonly antibiotic used was cefazolin and antibiotic choices were appropriate in 104 of 168 surgical procedures (62%). Gentamicin, metronidazole and ceftriaxone were the most frequently antibiotics that used inappropriately. Only in 100 of 168 procedures, duration was concordant with the ASHP guideline, whereas in 68 procedures, duration was longer than recommended time. In 98 procedures, the dose was lower and in one procedure, it was higher than recommended doses.Conclusion: Although such guidelines have been in place for many years, studies showed that much inappropriate antibiotic use as prophylaxis and poor adherence to guidelines are still major issues. It is essential for surgeons to be aware to consider the best antibiotic choices, dose and duration based on reliable guidelines for antibiotic prophylaxis.

Efficacy of a local‑drug delivery gel containing extracts of Quercus brantii and Coriandrum sativum as an adjunct to scaling and root planing in moderate chronic periodontitis patients

. Jaber Yaghini; . Mohammad Shahabooei; . Abolfazl Aslani; . Mozhgan Reza Zadeh; . Sima Kiani; . Narges Naghsh

Volume 3, Issue 2 , April 2014, Pages 67-71

Abstract

Objective: Recent advances in the field of alternative medicine introduced various herbal products for the treatment of periodontitis. The purpose of this study was to evaluate ... Read More

Ceftriaxone induced drug rash with eosinophilia and systemic symptoms

. Vivek S. Guleria; . Mukesh Dhillon; . Shaman Gill; . Nardeep Naithani

Volume 3, Issue 2 , April 2014, Pages 72-74

Abstract

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a drug reaction commonly occurring in association with aromatic anticonvulsants and allopurinol. It is characterized ... Read More

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Volume & Issue: Volume 3, Issue 2, April 2014

Evaluation of medicine prescription pattern using World Health Organization prescribing indicators in Iran: A cross‑sectional study

Abstract

Identification and management of adverse effects of antipsychotics in a tertiary care teaching hospital

Abstract

Education alone is not enough in ventilator associated pneumonia care bundle compliance

Abstract

Assessing health conditions and medication use among the homeless community in Long Beach, California

Abstract

Adherence to American society of health‑system pharmacists surgical antibiotic prophylaxis guidelines in a teaching hospital

Abstract

Efficacy of a local‑drug delivery gel containing extracts of Quercus brantii and Coriandrum sativum as an adjunct to scaling and root planing in moderate chronic periodontitis patients

Abstract

Ceftriaxone induced drug rash with eosinophilia and systemic symptoms

Abstract