Document Type : Original Article
Authors
- . Jaber Yaghini 1
- . Mohammad Shahabooei 1
- . Abolfazl Aslani 2
- . Mozhgan Reza Zadeh 3
- . Sima Kiani 1
- . Narges Naghsh 1
1 Department of Periodontology, Torabinejad Dental Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
2 Department of Pharmaceutics and Novel Drug Delivery Systems Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
3 School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract
Objective: Recent advances in the field of alternative medicine introduced various herbal
products for the treatment of periodontitis. The purpose of this study was to evaluate the
effects of combined extracts from Quercus brantii and Coriandrum sativum on periodontal
indices in adult periodontitis patients.
Methods: In this randomized, double‑blinded clinical trial, performed in Isfahan Dental
School in 2012, a new herbal medicament containing combined extracts from Q. brantii and
C. sativum was formulated in the gel form for subgingival application. Following scaling
and root planing (SRP), both herbal and placebo gels were delivered at the experimental
and control sites, respectively. Periodontal pocket depth, clinical attachment level, papilla
bleeding index, and plaque index were measured at baseline, 1 month and 3 months later.
Both intra‑and inter‑groups changes were registered. The obtained data were analyzed by
SPSS software, using repeated measure analysis of variance, paired t‑test, Mann-Whitney,
Friedman, and Wilcoxon tests. Differences with P < 0.05 were considered to be significant.
Findings: Both groups indicated statistically significant improvements in the periodontal
indices (P < 0.05), but there were no significant differences between two study groups with
this regard.
Conclusion: The herbal gel does not have considerable advantages over SRP alone as an
adjunct in periodontal treatment.
Keywords
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