Journal of Research in Pharmacy Practice

Objective: As chief prescribers, physicians could have a key role in rational drug use. Core prescribing indicators of all physicians have been evaluated in the Islamic Republic ... Read More

Evaluation of productivity in Iranian pharmaceutical companies: A DEA-based Malmquist approach and panel data analysis

. Mehdi Varmaghani; . Amir Hashemi Meshkini; . Farshad Farzadfar; . Mehdi Yousefi; . Saeed Yaghoubifard; . Vida Varahrami; . Ehsan Rezaei Darzi; . Majid Anabi; . Abbas Kebriaeezadeh; . Hedieh-Sadat Zekri

Volume 4, Issue 2 , April 2015, Pages 51-56

Abstract

Objective: In this study, we aimed to assess comparative productivity of 21 pharmaceutical companies in Iran during 2000–2013.Methods: To evaluate the productivity trend ... Read More

The comparative study of intravenous Ondansetron and sub-hypnotic Propofol dose in control and treatment of intrathecal Sufentanil-induced pruritus in elective caesarean surgery

. Anahita Hirmanpour; . Mohammadreza Safavi; . Azim Honarmand; . Akram Zavaran Hosseini; . Maryam Sepehrian

Volume 4, Issue 2 , April 2015, Pages 57-63

Abstract

Objective: Pruritus is a common and disturbing side effect of neuraxial opioids after cesarean section. The purpose of this study was to compare the efficacy of intravenous ondansetron ... Read More

Identification of possible adverse drug reactions in clinical notes: The case of glucose-lowering medicines

. Pernille Warrer; . Peter Bjødstrup Jensen; . Lise Aagaard; . Lars Juhl Jensen; . Søren Brunak; . Malene Hammer Krag; . Peter Rossing; . Thomas Almdal; . Henrik Ullits Andersen; . Ebba Holme Hansen

Volume 4, Issue 2 , April 2015, Pages 64-72

Abstract

Objective: Through manual review of clinical notes for patients with type 2 diabetes mellitus attending a Danish diabetes center, the aim of the study was to identify adverse drug reactions(ADRs) ... Read More

Usefulness of Danaparoid sodium in patients with Heparin-induced thrombocytopenia after cardiac surgery

. Farzaneh Foroughinia; . Fariborz Farsad; . Kheirollah Gholami; . Somayeh Ahmadi

Volume 4, Issue 2 , April 2015, Pages 73-78

Abstract

Objective: Thrombocytopenia is a common problem in cardiovascular surgery patients. However, heparin-induced thrombocytopenia (HIT) is a rare but life-threatening complication of ... Read More

Different doses of intravenous Magnesium sulfate on cardiovascular changes following the laryngoscopy and tracheal intubation: A double-blind randomized controlled trial

. Azim Honarmand; . Mohammadreza Safavi; . Sajad Badiei; . Neda Daftari-Fard

Volume 4, Issue 2 , April 2015, Pages 79-84

Abstract

Objective: Laryngoscopy and intratracheal intubation may cause acute hemodynamic instabilities due to catecholamine release. Magnesium sulfate (MgSO4) prevents catecholamine release ... Read More

Polypharmacy in the elderly

. Negar Golchin; . Scott H. Frank; . April Vince; . Lisa Isham; . Sharon B. Meropol

Volume 4, Issue 2 , April 2015, Pages 85-88

Abstract

Objective: The objective was to assess the frequency of polypharmacy and potential complications among local seniors.Methods: A cross-sectional convenience sample of 59 adults ... Read More

Midazolam premedication for Ketamine-induced emergence phenomenon: A prospective observational study

. Deepa Kameswari Perumal; . Mangaiarkkarasi Adhimoolam; . Nitya Selvaraj; . Suneeth Pullikotil Lazarus; . Meher Ali Raja Mohammed

Volume 4, Issue 2 , April 2015, Pages 89-93

Abstract

Objective: Ketamine administration is known to induce hemodynamic pressor response and psychomimetic effects which could be attenuated by appropriate premedication. The present ... Read More Objective: Ketamine administration is known to induce hemodynamic pressor response and psychomimetic effects which could be attenuated by appropriate premedication. The present study was designed to evaluate the effect of midazolam on hemodynamic stability and postoperative emergence phenomenon following ketamine anesthesia.Methods: This was a prospective observational study including 30 adult patients with American Society of Anesthesiologists physical grades I and II scheduled for elective short surgeries under ketamine anesthesia. Patients were premedicated with midazolam (0.02 mg/kg intravenously) before the ketamine induction (1 mg/kg intravenously). Demographic data and hemodynamic variables were observed during the perioperative period. Pain score by visual analog scale score and psychomimetic effects were recorded postoperatively.Findings: The mean ± standard deviation of heart rate, systolic blood pressure, diastolic blood pressure, and respiratory rate were decreased postoperatively (85.3 ± 11.4, 120.7 ± 8.2, 79.2 ± 5.5, 13.5 ± 1.8, respectively) compared to intraoperative period (88.53 ± 14.1, 123.83 ± 13.8, 83 ± 9.1, 14.13 ± 2.0, respectively). There was statistically significant decrease in systolic (P = 0.03) and diastolic (P = 0.002) blood pressure, but not with heart rate and respiratory rate. Eighty percent of patients had no pain at ½ hour and 1 hour, while this increased to 90% at 2 hours postoperatively. Mild emergence delirium was noted in 13.3% and 16.7% at ½ hour and 1 hour, respectively, which decreased to 13.3% at 2 hours. Dreams were noticed in 20%, 27% and 10% of patients at ½ hour, 1 and 2 hours after surgery, respectively.Conclusion: Midazolam premedication in ketamine anesthesia effectively attenuated the hemodynamic pressor response and postoperative emergence phenomenon. Hence, the combination of midazolam with ketamine can be safely used for short surgical painful procedures in adults.

Knowledge, awareness, and perception of contraception among senior pharmacy students in Malaysia: A pilot study

. Ramadan M. Elkalmi; . Muhammad Umair Khan; . Akram Ahmad; . Akshaya B. Srikanth; . Norny Syafinase Abdurhaman; . Shazia Q. Jamshed; . Ammar Ihsan Awad; . Hazrina Binti Ab Hadi

Volume 4, Issue 2 , April 2015, Pages 94-98

Abstract

Objective: This study aimed to assess the knowledge, awareness, and perception of contraception among senior pharmacy students of a public sector university in Malaysia.Methods: ... Read More

Multiple cutaneous necrotic lesions associated with Interferon beta-1b injection for multiple sclerosis treatment: A case report and literature review

. Gita Faghihi; . Akram Basiri; . Mohsen Pourazizi; . Bahareh Abtahi-Naeini; . Ali Saffaei

Volume 4, Issue 2 , April 2015, Pages 99-103

Abstract

Multiple sclerosis (MS) is a chronic and debilitating inflammatory autoimmune disorder of the central nervous system. MS patients may experience severe local inflammatory skin ... Read More

Journal of Research in Pharmacy Practice

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Volume & Issue: Volume 4, Issue 2, April 2015

Comparison of prescribing indicators of academic versus nonacademic specialist physicians in Urmia, Iran

Abstract

Evaluation of productivity in Iranian pharmaceutical companies: A DEA-based Malmquist approach and panel data analysis

Abstract

The comparative study of intravenous Ondansetron and sub-hypnotic Propofol dose in control and treatment of intrathecal Sufentanil-induced pruritus in elective caesarean surgery

Abstract

Identification of possible adverse drug reactions in clinical notes: The case of glucose-lowering medicines

Abstract

Usefulness of Danaparoid sodium in patients with Heparin-induced thrombocytopenia after cardiac surgery

Abstract

Different doses of intravenous Magnesium sulfate on cardiovascular changes following the laryngoscopy and tracheal intubation: A double-blind randomized controlled trial

Abstract

Polypharmacy in the elderly

Abstract

Midazolam premedication for Ketamine-induced emergence phenomenon: A prospective observational study

Abstract

Knowledge, awareness, and perception of contraception among senior pharmacy students in Malaysia: A pilot study

Abstract

Multiple cutaneous necrotic lesions associated with Interferon beta-1b injection for multiple sclerosis treatment: A case report and literature review

Abstract