Journal of Research in Pharmacy Practice

Objective: Any operation leads to body stress and tissue injury that causes pain and its complications. Glucocorticoids such as Dexamethasone are strong anti‑inflammatory agents, ... Read More

Total Phenytoin concentration is not well correlated with active free drug in critically-ill head trauma patients

. Kourosh Sadeghi; . Farin Hadi; . Arezoo Ahmadi; . Hadi Hamishehkar; . Mohammad‑Taghi Beigmohammadi5; . Ata Mahmoodpoor; . Mohammad Reza Rouini; . Shirin Farhudi; . Narjes Hendoui; . Atabak Najafi; . Mojtaba Mojtahedzadeh

Volume 2, Issue 3 , July 2013, Pages 106-109

Abstract

Objective: Phenytoin is an antiepileptic drug used widely for prophylaxis and treatment of seizure after neurotrauma. Phenytoin has a complex pharmacokinetics and monitoring of ... Read More

ST‑T segment changes in patients with tricyclic antidepressant poisoning

. Farzad Gheshlaghi; . Mozhgan Karbalayi Mehrizi; . Ahmad Yaraghi; . Ali Mohammad Sabzghabaee; . Forough Soltaninejad; . Nastaran Eizadi-Mood

Volume 2, Issue 3 , July 2013, Pages 110-113

Abstract

Objective: Tricyclic antidepressant (TCA) poisoning is among highly prevalent and potentially dangerous toxicities. ST‑T changes are observed in the electrocardiogram (ECG) of ... Read More

Health‑care cost of diabetes in South India: A cost of illness study

. Sadanandam Akari; . Uday Venkat Mateti; . Buchi Reddy Kunduru

Volume 2, Issue 3 , July 2013, Pages 114-117

Abstract

Objective: The objective of this study is to analyze the health‑care cost by calculating the direct and indirect costs of diabetes with co‑morbidities in south India. Methods: ... Read More

Frequency and types of the medication errors in an academic emergency department in Iran: The emergent need for clinical pharmacy services in emergency departments

. Alireza Zeraatchi; . Mohammad‑Taghi Talebian; . Amir Nejati; . Simin Dashti‑Khavidaki

Volume 2, Issue 3 , July 2013, Pages 118-122

Abstract

Objective: Emergency departments (EDs) are characterized by simultaneous care of multiple patients with various medical conditions. Due to a large number of patients with complex ... Read More Objective: Emergency departments (EDs) are characterized by simultaneous care of multiple patients with various medical conditions. Due to a large number of patients with complex diseases, speed and complexity of medication use, working in under‑staffing and crowded environment, medication errors are commonly perpetrated by emergency care providers. This study was designed to evaluate the incidence of medication errors among patients attending to an ED in a teaching hospital in Iran.Methods: In this cross‑sectional study, a total of 500 patients attending to ED were randomly assessed for incidence and types of medication errors. Some factors related to medication errors such as working shift, weekdays and schedule of the educational program of trainee were also evaluated.Findings: Nearly, 22% of patients experienced at least one medication error. The rate of medication errors were 0.41 errors per patient and 0.16 errors per ordered medication. The frequency of medication errors was higher in men, middle age patients, first weekdays, night‑time work schedules and the first semester of educational year of new junior emergency medicine residents. More than 60% of errors were prescription errors by physicians and the remaining were transcription or administration errors by nurses. More than 35% of the prescribing errors happened during the selection of drug dose and frequency. The most common medication errors by nurses during the administration were omission error (16.2%) followed by unauthorized drug (6.4%). Most of the medication errors happened for anticoagulants and thrombolytics (41.2%) followed by antimicrobial agents (37.7%) and insulin (7.4%).Conclusion: In this study, at least one‑fifth of the patients attending to ED experienced medication errors resulting from multiple factors. More common prescription errors happened during ordering drug dose and frequency. More common administration errors included dug omission or unauthorized drug.

Pharmacist involvement in the patient care improves outcome in hypertension patients

. Pranay Wal; . Ankita Wal; . Anil Bhandari; . Ummeshwar Pandey; . Awani K Rai

Volume 2, Issue 3 , July 2013, Pages 123-129

Abstract

Objective: The main objective of this study was to assess the effects of pharmaceutical care interventions in patients with essential hypertension in Lakshmi Pat Singhania Institute of ... Read More

Methadone toxicity in a poisoning referral center

. Fatemeh Taheri; . Ahmad Yaraghi; . Ali Mohammad Sabzghabaee; . Maryam Moudi; . Nastaran Eizadi‑Mood; . Farzad Gheshlaghi; . Ziba Farajzadegan

Volume 2, Issue 3 , July 2013, Pages 130-134

Abstract

Objective: Methadone poisoning can occur accidentally or intentionally for suicide or homicide purposes. The aim of this study was to evaluate the epidemiological and clinical manifestations ... Read More Objective: Methadone poisoning can occur accidentally or intentionally for suicide or homicide purposes. The aim of this study was to evaluate the epidemiological and clinical manifestations of Methadone poisoning.Methods: A descriptive analytical study was performed from 2010 to 2012 in the poisoning emergency and clinical toxicology departments of Noor hospital affiliated with Isfahan University of Medical Sciences (Isfahan, Iran). All patients with Methadone poisoning within this period of time were investigated. Different variables were recorded in a checklist.Findings: A total of 385 patients were studied. About 85.7% had ingested only Methadone and 14.3% had ingested other medications with Methadone. Mean ± standard deviation of the age was 32.1 ± 15 years (range: 1‑90). Most of the patients were male (76.4%). Nearly 40% of the patients were narcotic addicts, 25.5% were addicts under surveillance of Methadone maintenance therapy centers and 34.5% were non‑addicts. Intentional poisoning was observed in most of the patients (57.7%). Most of the patients had a low level of consciousness on admission (58.2%). Respiratory depression and hypotension was observed in 35.6% and 12.7% of the cases as the most common symptoms. Regarding vital signs, there was a significant difference in respiratory rate on admission among different evaluated groups (P = 0.02). Length of hospital stay was 18.79 ± 0.72 h (range: 4‑240 h, median: 15 h). About 57 patients (25.8%) from the intentionally poisoned patients and 19 patients (12.3%) from the unintentionally poisoned patients had a history of psychiatric disorder (P = 0.001). Most of the patients survived without complications.Conclusion: Addiction, age, gender, attempt to suicide and a history of psychiatric disorder were of the most important factors effective in Methadone poisoning, which should be considered in the public training and prevention of poisoning.

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Volume & Issue: Volume 2, Issue 3, July 2013

Cross cultural adaptation and validation of the Stanford health assessment questionnaire in patients with rheumatoid arthritis: Current scenario and future prospects

Abstract

The effect of intravenous Dexamethasone on post‑cesarean section pain and vital signs: A double‑blind randomized clinical trial

Abstract

Total Phenytoin concentration is not well correlated with active free drug in critically-ill head trauma patients

Abstract

ST‑T segment changes in patients with tricyclic antidepressant poisoning

Abstract

Health‑care cost of diabetes in South India: A cost of illness study

Abstract

Frequency and types of the medication errors in an academic emergency department in Iran: The emergent need for clinical pharmacy services in emergency departments

Abstract

Pharmacist involvement in the patient care improves outcome in hypertension patients

Abstract

Methadone toxicity in a poisoning referral center

Abstract