Document Type : Original Article
Authors
1 Department of Emergency Medicine, Tehran University of Medical Science, Tehran, Iran
2 Department of Clinical Pharmacy, Tehran University of Medical Science, Tehran, Iran
Abstract
Objective: Emergency departments (EDs) are characterized by simultaneous care of
multiple patients with various medical conditions. Due to a large number of patients with
complex diseases, speed and complexity of medication use, working in under‑staffing and
crowded environment, medication errors are commonly perpetrated by emergency care
providers. This study was designed to evaluate the incidence of medication errors among
patients attending to an ED in a teaching hospital in Iran.
Methods: In this cross‑sectional study, a total of 500 patients attending to ED were randomly
assessed for incidence and types of medication errors. Some factors related to medication
errors such as working shift, weekdays and schedule of the educational program of trainee
were also evaluated.
Findings: Nearly, 22% of patients experienced at least one medication error. The rate of
medication errors were 0.41 errors per patient and 0.16 errors per ordered medication. The
frequency of medication errors was higher in men, middle age patients, first weekdays, night‑time
work schedules and the first semester of educational year of new junior emergency medicine
residents. More than 60% of errors were prescription errors by physicians and the remaining
were transcription or administration errors by nurses. More than 35% of the prescribing
errors happened during the selection of drug dose and frequency. The most common
medication errors by nurses during the administration were omission error (16.2%) followed
by unauthorized drug (6.4%). Most of the medication errors happened for anticoagulants and
thrombolytics (41.2%) followed by antimicrobial agents (37.7%) and insulin (7.4%).
Conclusion: In this study, at least one‑fifth of the patients attending to ED experienced
medication errors resulting from multiple factors. More common prescription errors
happened during ordering drug dose and frequency. More common administration errors
included dug omission or unauthorized drug.
Keywords
1. Williams DJ. Medication errors. J R Coll Physicians Edinb
2007;37:343‑6.
2. Ferner RE, Aronson JK. Clarification of terminology in
medication errors: Definitions and classification. Drug Saf
2006;29:1011‑22.
3. Peth HA Jr. Medication errors in the emergency department:
A systems approach to minimizing risk. Emerg Med Clin
North Am 2003;21:141‑58.
4. Kohn L, Corrigan J, Donaldson M. To Err is Human: Building
a Safer Health System. Washington, DC: National Academic
Press; 2000.
5. Fordyce J, Blank FS, Pekow P, Smithline HA, Ritter G,
Gehlbach S, et al. Errors in a busy emergency department.
Ann Emerg Med 2003;42:324‑33.
6. Schenkel S. Promoting patient safety and preventing
medical error in emergency departments. Acad Emerg Med
2000;7:1204‑22.
7. Institute of Medicine. Hospital‑Based Emergency Care: At the
Breaking Point. Washington, DC: National Academy Press; 2006.
8. Chin MH, Wang LC, Jin L, Mulliken R, Walter J, Hayley DC,
et al. Appropriateness of medication selection for older persons
in an urban academic emergency department. Acad Emerg
Med 1999;6:1232‑42.
9. Caterino JM, Emond JA, Camargo CA Jr. Inappropriate
medication administration to the acutely ill elderly:
A nationwide emergency department study, 1992‑2000. J Am
Geriatr Soc 2004;52:1847‑55.
10. Glossary of terms related to patient and medication safety.
Available from: http://www.bvs.org.ar/pdf/seguridadpaciente.
pdf. [Last updated on 2005 Oct 20, Last cited on 2011 Nov 18].
11. Pham JC, Story JL, Hicks RW, Shore AD, Morlock LL,
Cheung DS, et al. National study on the frequency, types,
causes, and consequences of voluntarily reported emergency
department medication errors. J Emerg Med 2011;40:485‑92.
12. Rothschild JM, Churchill W, Erickson A, Munz K,
Schuur JD, Salzberg CA, et al. Medication errors recovered
by emergency department pharmacists. Ann Emerg Med
2010;55:513‑21.
13. Kozer E, Scolnik D, Macpherson A, Keays T, Shi K, Luk T,
et al. Variables associated with medication errors in pediatric
emergency medicine. Pediatrics 2002;110:737‑42.
14. Khalili H, Farsaei S, Rezaee H, Dashti‑Khavidaki S. Role of
clinical pharmacists’ interventions in detection and prevention
of medication errors in a medical ward. Int J Clin Pharm
2011;33:281‑4.
15. Khalili H, Karimzadeh I, Mirzabeigi P, Dashti‑Khavidaki S.
Evaluation of clinical pharmacist’s interventions in an
infectious diseases ward and impact on patient’s direct
medication cost. Eur J Intern Med 2013;24:227‑33.
16. Vessal G. Detection of prescription errors by a unit‑based
clinical pharmacist in a nephrology ward. Pharm World Sci
2010;32:59‑65.
17. Dashti‑Khavidaki S, Khalili H, Hamishekar H, Shahverdi S.
Clinical pharmacy services in an Iranian teaching hospital:
A descriptive study. Pharm World Sci 2009;31:696‑700.
18. Kaboli PJ, Hoth AB, McClimon BJ, Schnipper JL. Clinical
pharmacists and inpatient medical care: Asystematic review.
Arch Intern Med 2006;166:955‑64.