Drug rash with eosinophilia and systemic symptoms syndrome is an idiosyncratic drug reaction characterized by fever, skin eruption, lymph node enlargement, and internal organ involvement. We report a case of a patient with pneumonia who developed clinical manifestations of fever, rash, lymphadenopathy, hypereosinophilia, and visceral involvement (renal failure and eosinophilic pneumonitis) caused by methimazole. The patient improved remarkably with drug withdrawal. A high index of clinical suspicion is emphasized to facilitate prompt diagnosis of medication-related adverse effect and its discontinuation.
Jin,H , Wang,L and Ye,J . (2017). Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism. Journal of Research in Pharmacy Practice, 6(2), 130-133.
MLA
Jin,H , , Wang,L , and Ye,J . "Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism", Journal of Research in Pharmacy Practice, 6, 2, 2017, 130-133.
HARVARD
Jin H, Wang L, Ye J. (2017). 'Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism', Journal of Research in Pharmacy Practice, 6(2), pp. 130-133.
CHICAGO
H Jin, L Wang and J Ye, "Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism," Journal of Research in Pharmacy Practice, 6 2 (2017): 130-133,
VANCOUVER
Jin H, Wang L, Ye J. Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism. Journal of Research in Pharmacy Practice. 2017;6(2):130-133.