Drug rash with eosinophilia and systemic symptoms syndrome is an idiosyncratic drug reaction characterized by fever, skin eruption, lymph node enlargement, and internal organ involvement. We report a case of a patient with pneumonia who developed clinical manifestations of fever, rash, lymphadenopathy, hypereosinophilia, and visceral involvement (renal failure and eosinophilic pneumonitis) caused by methimazole. The patient improved remarkably with drug withdrawal. A high index of clinical suspicion is emphasized to facilitate prompt diagnosis of medication-related adverse effect and its discontinuation.
Jin,H. , Wang,L. and Ye,J. (2017). Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism. Journal of Research in Pharmacy Practice, 6(2), 130-133.
MLA
Jin,H. , , Wang,L. , and Ye,J. . "Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism", Journal of Research in Pharmacy Practice, 6, 2, 2017, 130-133.
HARVARD
Jin H., Wang L., Ye J. (2017). 'Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism', Journal of Research in Pharmacy Practice, 6(2), pp. 130-133.
CHICAGO
H. Jin, L. Wang and J. Ye, "Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism," Journal of Research in Pharmacy Practice, 6 2 (2017): 130-133,
VANCOUVER
Jin H., Wang L., Ye J. Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism. Journal of Research in Pharmacy Practice, 2017; 6(2): 130-133.
