Drug rash with eosinophilia and systemic symptoms syndrome is an idiosyncratic drug reaction characterized by fever, skin eruption, lymph node enlargement, and internal organ involvement. We report a case of a patient with pneumonia who developed clinical manifestations of fever, rash, lymphadenopathy, hypereosinophilia, and visceral involvement (renal failure and eosinophilic pneumonitis) caused by methimazole. The patient improved remarkably with drug withdrawal. A high index of clinical suspicion is emphasized to facilitate prompt diagnosis of medication-related adverse effect and its discontinuation.
Jin, H., Wang, L. & Ye, J. (2017). Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism. Journal of Research in Pharmacy Practice, 6(2), 130–133.
MLA
Jin, H., Wang, L., & Ye, J. "Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism", Journal of Research in Pharmacy Practice, 6, 2, 2017, 130–133.
HARVARD
Jin, H., Wang, L., & Ye, J. (2017). 'Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism', Journal of Research in Pharmacy Practice, 6(2), pp. 130–133.
CHICAGO
Jin, H., Wang, L. & Ye, J., "Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism." Journal of Research in Pharmacy Practice, 6 2 (2017): 130–133,
VANCOUVER
Jin H., Wang L., Ye J. Drug reaction with eosinophilia and systemic symptom in a patient with pneumonia and hyperthyroidism. Journal of Research in Pharmacy Practice. 2017;6(2):130–133.
