Journal of Research in Pharmacy Practice

Zika virus: An emerging epidemic

Anna Ratanacharoensiri; Luke Huggins; Mark Johnson; Isha Patel

Volume 6, Issue 1 , January 2017, Pages 1-2

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A copmarative review of electronic prescription systems: Lessons learned from developed countries

Mahnaz Samadbeik; Maryam Ahmadi; Farahnaz Sadoughi; Ali Garavand

Volume 6, Issue 1 , January 2017, Pages 3-11

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This review study aimed to compare the electronic prescription systems in five selected countries (Denmark, Finland, Sweden, England, and the United States). Compared developed countries ... Read More

Quetiapine misuse and abuse: Is it an atypical paradigm of drug seeking behavior?

Sean Kim; Gayoung Lee; Eric Kim; Hyejin Jung; Jongwha Chang

Volume 6, Issue 1 , January 2017, Pages 12-15

Abstract

Recent case reports in medical literatures suggest that more and more second-generation atypical antipsychotics (AAs) have been prescribed for off-label use; quetiapine (Brand name: ... Read More

The effect of Vitamin D administration on intracellular adhesion molecule-1 and vascular cell adhesion molecule-1 levels in hemodialysis patients: A placebo-controlled, double-blinded clinical trial

Afsoon Emami Naeini; Firouzeh Moeinzadeh; Sahar Vahdat; Akbar Ahmadi; Zahra Parin Hedayati; Safoora Shahzeidi

Volume 6, Issue 1 , January 2017, Pages 16-20

Abstract

Vitamin D deficiency is quite common among end-stage renal disease (ESRD) patients, and Vitamin D administration could reduce morbidity and mortality in these patients through ... Read More

Patients'/clients' expectation toward and satisfaction from pharmacy services

Mohammed Biset Ayalew; Kaleab Taye; Daniel Asfaw; Bethlehem Lemma; Filagot Dadi; Habtamu Solomon; Haile Tazeze; Bayew Tsega

Volume 6, Issue 1 , January 2017, Pages 21-26

Abstract

Satisfaction is becoming a popular health-care quality indicator as it reflects the reality of service or care provided. The aim of this study was to assess the level of patients' ... Read More

The effects of statins on pulmonary artery pressure in patients with chronic obstructive pulmonary disease: A randomized controlled trial

Anahita Arian; Sayyed Gholamreza Mortazavi Moghadam; Toba Kazemi; Morteza Hajihosseini

Volume 6, Issue 1 , January 2017, Pages 27-30

Abstract

Pulmonary hypertension is a serious complication in patients suffering from chronic obstructive pulmonary disease (COPD). The aim of this study is to investigate the effects of atorvastatin ... Read More

Cytopenia occurrence in kidney transplant recipients within early post-transplant period

Atefeh Jafari; Parisa Najivash; Mohammad-Reza Khatami; Simin Dashti-Khavidaki

Volume 6, Issue 1 , January 2017, Pages 31-39

Abstract

This study assessed incidence, severity, and time to occurrence of drug-induced leukopenia/thrombocytopenia within 1st month after kidney transplantation.Methods: This cross-sectional ... Read More This study assessed incidence, severity, and time to occurrence of drug-induced leukopenia/thrombocytopenia within 1st month after kidney transplantation.Methods: This cross-sectional study was conducted on newly kidney transplant recipients from two hospitals, Iran. Patients with thrombocytopenia due to acute antibody-mediated rejection were excluded from the study. Demographic, clinical, and laboratory data of patients within the 1st month after transplantation were collected.Findings: Of 213 patients, 14.1% and 66.2% experienced leukopenia and thrombocytopenia, respectively. Cytopenia happened more commonly among patients with thymoglobulin-containing regimen (for leukopenia: 24.6% vs. 0%, P < 0.001; for thrombocytopenia 84.4% vs. 41.8%, P < 0.001). Most leukopenia patients experienced Grades 1 and 2 of leukopenia (46.6% and 40% of patients). Most thrombocytopenic patients showed Grade 1 of thrombocytopenia (78.7%). Cumulative dose of thymoglobulin did not differ between patients with and without leukopenia (5.57 ± 1.13 vs. 5.9 ± 1.96 mg/kg; P = 0.613) or with and without thrombocytopenia (5.87 ± 1.86 vs. 5.56 ± 1.38 mg/kg; P = 0.29). Cytopenia were more common among recipients from deceased compared with from living donors (91.3% vs. 8.7% for leukopenia patients, P = 0.001; 69.9% vs. 33.1% for thrombocytopenia, P = 0.02). More patients with kidney from deceased donors received thymoglobulin in their immunosuppressive regimen (82% vs. 37%; P < 0.001). The median time to leukopenia and thrombocytopenia were 3 days and 1 day, respectively.Conclusion: Among immunosuppressive and prophylactic antimicrobial agents, thymoglobulin is more related to cytopenia; therefore, thymoglobulin dose reduction is recommended as the first intervention to manage cytopenia without need for reduction of its cumulative dose. The higher prevalence of cytopenia among recipients from deceased donors may be related to the higher use of thymoglobulin in these patients.

Growth hormone utilization review in a pediatric primary care setting

Fatemeh Sayarifard; Fereshteh Bakhshi Imcheh; Shirinsadat Badri; Toktam Faghihi; Mostafa Qorbani; Mania Radfar

Volume 6, Issue 1 , January 2017, Pages 40-43

Abstract

One of the main problems facing public health providers and administrators in many countries is ensuring the rational use of high-cost drugs. In this regard, on-going process of medication ... Read More One of the main problems facing public health providers and administrators in many countries is ensuring the rational use of high-cost drugs. In this regard, on-going process of medication use evaluation can be considered as a useful tool. In this study, we evaluated certain usage aspects of a highly-cost medication, that is, recombinant growth hormone (GH).Methods: This cross-sectional study conducted from August 2012 to August 2014. Children receiving GH ± gonadotropin releasing hormone (GnRH) analogs were included in the study. A researcher-designed checklist was developed to evaluate the GH utilization in these patients. Baseline demographic characteristics and background clinical and growth data, as well as any aspects of drug therapy including indications, dosing, monitoring, and discontinuation were collected from the patients' medical records.Findings: Seventy children receiving GH entered the study, of which 23 patients (32.85%) received GH and GnRH analogs simultaneously. At the baseline, 67 children (95.7%) had GH stimulation test, whereas serum insulin-like growth factor-1 (IGF-1) levels were measured in 63 (90%) patients. Sixty-seven patients (95.71%) had thyroid function test, whereas bone age was determined in 68 children (97.14%). The mean ± standard deviation of GH dose for idiopathic short stature, GH deficiency, Turner's syndrome and born small for gestational age in our study was 0.22 ± 0.025 mg/kg/week, 0.23 ± 0.04 mg/kg/week, 0.22 ± 0.015 mg/kg/week, and 0.23 ± 0.02 mg/kg/week, respectively. Height and weight of all patients were followed every 3–6 months, regularly. Thirty patients were treated with GH for at least 1 year, of which thyroid hormones and IGF-1 levels were measured annually in 25 (83.33%) and 26 (86.66%) patients, respectively; while bone age was evaluated in 13 (43.33%) children, annually. GH treatment was discontinued in 15 patients (21.42%), while financial problem was the major reason.Conclusion: Diagnostic tests and monitoring of height, weight, IGF-1 level and thyroid function was properly performed in this setting. However, a number of patients with ISS and Turner's syndrome were under-dosed.

Clinical response and outcome in patients with multidrug resistant gram-negative infections

Masoume Malekolkottab; Lida Shojaei; Hossein Khalili; Mahsa Doomanlou

Volume 6, Issue 1 , January 2017, Pages 44-51

Abstract

In this study, frequency and antimicrobial sensitivity pattern of multidrug resistant (MDR) microorganisms were evaluated in a referral teaching hospital in Iran.Methods: Patients ... Read More

The content of plasma selenium in early admitted septic patients

Omid Moradi Moghaddam; Mohammad Niakan Lahiji; Azadeh Moghaddas; Maryam Farasatinasab; Somayyeh Nasiripour

Volume 6, Issue 1 , January 2017, Pages 52-55

Abstract

Selenium depletion has been reported in critical illness correlates with an increase in mortality and morbidity. In this study, we aimed to access the selenium plasma levels of septic ... Read More

A novel practical equation for treatment of emergent hypernatremia and dehydration phase in infants

Saba Ghaffary; Azadeh Moghaddas; Mehrnoush Dianatkhah

Volume 6, Issue 1 , January 2017, Pages 56-59

Abstract

Serum sodium (Na) concentration more than 145 mmol/L is defined as hypernatremia. Hypernatremia carries an acute morbidity and mortality, especially in neonates and infants. Rapid correction ... Read More

Determination of vancomycin-resistant Staphylococcus aureus

Farzane Ghasabi; Mehrdad Halaji; Samereh Nouri

Volume 6, Issue 1 , January 2017

Abstract

Drug-drug interactions: The importance of medication reconciliation

Mahin Jamshidi Makiani; Somayyeh Nasiripour; Mahnaz Hosseini; Alireza Mahbubi

Volume 6, Issue 1 , January 2017

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Erratum: A new approach to vancomycin utilization evaluation: A cross-sectional study in intensive care unit

Volume 6, Issue 1 , January 2017

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Volume 11 (2022)

Volume 10 (2021)

Volume 9 (2020)

Volume 8 (2019)

Volume 7 (2018)

Volume 6 (2017)

Volume 5 (2016)

Volume 4 (2015)

Volume 3 (2014)

Volume 2 (2013)

Volume 1 (2012)

Volume & Issue: Volume 6, Issue 1, January 2017, Pages 1-63

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