Journal of Research in Pharmacy Practice

The Second Euro‑Asian Congress of Pharmacoepidemiology Recently Held in Tehran 2019

Volume 9, Issue 1 , January 2020, Pages 1-2

Abstract

Pharmacist interventions in improving clinical outcomes in patients with type 2 diabetes mellitus among the underrepresented population: A collaborative ambulatory care pharmacy practice (CAPP) approach

Mok Thoong Chong

Volume 9, Issue 1 , January 2020, Pages 3-9

Abstract

The objective of this study was to evaluate the impact of pharmacist's interventions through a collaborative ambulatory care pharmacy practice (CAPP) model in patients with type ... Read More

Recurrence rate and clinical outcome of amniotic membrane transplantation combined with mitomycin c in pterygium surgery: Two-year follow-up

Hasan Razmjoo; Seyed-Abolfazl Kashfi; Majid Mirmohammadkhani; Mohsen Pourazizi

Volume 9, Issue 1 , January 2020, Pages 10-15

Abstract

To evaluate the recurrence rate and outcome of pterygium surgery with amniotic membrane transplantation (AMT) and intraoperative mitomycin C (MMC). Methods: This prospective ... Read More

Glycemic control after initiating direct-acting antiviral agents in patients with hepatitis C virus and type 2 diabetes mellitus using the united states integrated healthcare system

Alicia Halim Wong; John Sie; Angela Chen; Basuki Gunawan; Joanie Chung; Nazia Rashid

Volume 9, Issue 1 , January 2020, Pages 16-23

Abstract

Hepatitis C virus (HCV) has an increased risk of Type 2 diabetes mellitus (T2DM). Prior studies found that the eradication of HCV with direct-acting antiviral (DAA) agents led ... Read More

Adaptation and validation of the screening tool of older people's prescriptions instrument for the Indonesian population

Siti Fauziyah; Retnosari Andrajati; Ratu Ayu Dewi Sartika; Maksum Radji

Volume 9, Issue 1 , January 2020, Pages 24-29

Abstract

In this study, we aimed to prepare and validate an Indonesian version for the Screening Tool of Older People's Prescriptions (STOPP), which is an instrument to identify inappropriate ... Read More In this study, we aimed to prepare and validate an Indonesian version for the Screening Tool of Older People's Prescriptions (STOPP), which is an instrument to identify inappropriate medications for elderly patients. Methods: The Indonesian version of STOPP (STOPP_INA) was developed using modified transcultural adaptation guidelines from the American Academy of Orthopedic Surgeons. Our method consisted of translating original STOPP into Indonesian (forwardly translation), synthesis of forward translation, translation into English and synthesis of back translation, a review by the copyright holder of STOPP, a review by the expert team, pretest, revision of STOPP_INA, field test, and psychometric analysis of the final version of the questionnaire. The study design for this part was quasi-experimental with purposive sampling for members of the translator's team, expert's team, and respondents in the pretest, but they were different from field testing that used purposive and postsurvey sampling for respondents. Content validity and face validity were used to construct the validity of STOPP_INA by assessing item-level content validity and correlation between items and total values. Internal consistency was measured with Cronbach's alpha coefficient. Findings: The expert panel agreed on a list of 81 criteria. Five (62.50%) of expert team members agreed and could be continued to the field test without revision of STOPP_INA and 3 (37.50%) agreed with a revision. The research subjects in the psychometric test had 230 respondents, 5 (2.17%) resigned, with an average of item-level content validity index of 0.99. The construct validity analysis showed that 5-item criteria are “not valid,” namely in A1, A3, B7, B10, and C3. Reliability analysis showed the Cronbach's Alpha and Cronbach's Alpha Based on Standardized Items were 0.978 and 0.979. Conclusion: The expert team was be agreed on 81 criteria (100%) of adaptation of STOPP version 2 criteria. There were 5 criteria that not valid statistically, they could not be removed from the instrument because they can influence content and construct of the instrument. The STOPP_INA has been developed for the Indonesian population, currently being tested in clinical practice against elderly patients undergoing hospitalization.

Thiamine for prevention of postoperative delirium in patients undergoing gastrointestinal surgery: A randomized clinical trial

Rohollah Moslemi; Hossein Khalili; Mostafa Mohammadi; Zeinab Mehrabi; Niayesh Mohebbi

Volume 9, Issue 1 , January 2020, Pages 30-35

Abstract

Postoperative delirium is a common complication after gastrointestinal surgery that is associated with adverse outcomes. Thiamine is an essential cofactor for the glycolysis, oxidative ... Read More

Reducing missed medication doses in intensive care units: A pharmacist-led intervention

Mukhtar Jawad Alomar; Sohail Ahmad; Yahya Moustafa; Lafi Salim Alharbi

Volume 9, Issue 1 , January 2020, Pages 36-43

Abstract

The objectives of this study were to investigate the frequency and reasons for missing doses and impact of a pharmacist-led intervention to reduce the missed doses in intensive care ... Read More

Pediatric toxicoepidemiology of tramadol intoxication in Iran: A 5-year cross-sectional study

Mohaddeseh Hedayati Goudarzi; Nastaran Eizadi-Mood; Marjan Mansourian; Soroush Mohammadi-Jouabadi; Payam Peymani; Ali Mohammad Sabzghabaee

Volume 9, Issue 1 , January 2020, Pages 44-49

Abstract

We aimed to find the toxicoepidemiological indicators of tramadol poisoning in children and also the relationship of these indicators (such as demographic characteristics, and ... Read More We aimed to find the toxicoepidemiological indicators of tramadol poisoning in children and also the relationship of these indicators (such as demographic characteristics, and referral time) with the final therapeutic outcome. Methods: In this cross-sectional study with retrospective data collection, we included the records for all the patients under 18 that have been admitted due to tramadol poisoning between 2010 and 2015 to Noor and Ali-Asghar (PBUH) University hospital which serves as the referral medical center for acute poisonings management in the central part of Iran and is located in Isfahan. Demographic characteristics, ingested dose, dosage forms, clinical manifestations, coingested drugs, and the outcome of treatment for all pediatric patients were documented and descriptively analyzed. Findings: Demographic and clinical data of a total of 189 patients including 101 male (53.4%) with a mean age of 16.66 ± 2.64 years were abstracted and included in this study. The average time between tramadol ingestion and hospital admission was 3.39 ± 3.23 h. Mean duration of hospitalization was 12.3 ± 10.7 h. In all cases, the route of drug exposure was oral, and the most common form of drug dosage form was 100 mg tablets (n = 122) proceeded by 200 mg tablets (n = 32). The mean estimated dose of ingested tramadol was 1126 ± 1061 mg (median, 900 range, 50–7000 mg). 43.9% of the poisoned patients were high school students, and 23.3% had a high school diploma. Intentional intoxications were reported in 93.1% cases and 42.9% had coingestions. Activated charcoal (87.3%), gastric lavage (59.3%), oxygen therapy with mask (46.6%), naloxone (11.6%), anticonvulsants (13.2%), and intubation and ventilation (5.3%) were done as first-line therapeutic measures. Conclusion: Our results suggest that the trend of acute tramadol poisoning among children is decreasing, mostly accidental in adolescents and commonly intentional among young children. Proper education to improve emotional intelligence for young adults and to keep drugs out of reach of the children and safer packaging is recommended to reduce tramadol poisoning incidence in the pediatric population

Prospective study of irrational prescription of teicoplanin in a large academic hospital: A dilemma of antimicrobial resistance

Masoud Hajialigol; Shadi Farsaei; Kiana Shirani

Volume 9, Issue 1 , January 2020, Pages 50-55

Abstract

Teicoplanin is an antibiotic used to treat severe Gram-positive infections, especially those caused by methicillin-resistant Staphylococcus aureus(MRSA). In this study, we ... Read More

Reduced weekly subcutaneous doses of bortezomib in combination with cyclophosphamide and dexamethasone for newly diagnosed multiple myeloma

Farzaneh Ashrafi; Azadeh Moghaddas; Ali Darakhshandeh

Volume 9, Issue 1 , January 2020, Pages 56-59

Abstract

A combination of bortezomib, cyclophosphamide, and dexamethasone is highly effective in the treatment of newly diagnosed multiple myeloma. Neuropathy is a dose-limiting adverse ... Read More

The second Euro-Asian congress of pharmacoepidemiology recently held in Tehran 2019

Sten Olsson

Volume 9, Issue 1 , January 2020

Abstract

The necessity of an aseptic environment for the preparation of enteral feeding solutions in iranian hospitals

Ali Rismanbaf

Volume 9, Issue 1 , January 2020

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Volume & Issue: Volume 9, Issue 1, January 2020, Pages 1-60

The Second Euro‑Asian Congress of Pharmacoepidemiology Recently Held in Tehran 2019

Abstract

Pharmacist interventions in improving clinical outcomes in patients with type 2 diabetes mellitus among the underrepresented population: A collaborative ambulatory care pharmacy practice (CAPP) approach

Abstract

Recurrence rate and clinical outcome of amniotic membrane transplantation combined with mitomycin c in pterygium surgery: Two-year follow-up

Abstract

Glycemic control after initiating direct-acting antiviral agents in patients with hepatitis C virus and type 2 diabetes mellitus using the united states integrated healthcare system

Abstract

Adaptation and validation of the screening tool of older people's prescriptions instrument for the Indonesian population

Abstract

Thiamine for prevention of postoperative delirium in patients undergoing gastrointestinal surgery: A randomized clinical trial

Abstract

Reducing missed medication doses in intensive care units: A pharmacist-led intervention

Abstract

Pediatric toxicoepidemiology of tramadol intoxication in Iran: A 5-year cross-sectional study

Abstract

Prospective study of irrational prescription of teicoplanin in a large academic hospital: A dilemma of antimicrobial resistance

Abstract

Reduced weekly subcutaneous doses of bortezomib in combination with cyclophosphamide and dexamethasone for newly diagnosed multiple myeloma

Abstract

The second Euro-Asian congress of pharmacoepidemiology recently held in Tehran 2019

Abstract

The necessity of an aseptic environment for the preparation of enteral feeding solutions in iranian hospitals

Abstract