Authors
1 Department of Pharmacology and Therapeutics, Usmanu Danfodiyo University, Sokoto, Nigeria
2 Department of Community Medicine, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria
Abstract
Objective: Objective of this study was to assess the attitude of nurses and pharmacists
towards adverse drug reactions (ADRs) reporting.
Methods: The questionnaire was designed based on extended “Inman seven deadly
sins.” Two hundred and seventy‑two respondents were selected by stratified sampling
technique. The questionnaires were delivered to the respondents at their places of
practice. The data generated were analyzed by Sigma XL Software Inc.
Findings: There was no statistically significant relationship between demographic
profiles and reporting attitude except for qualification. On extended “Inman seven
deadly sins” awareness of reporting protocol and nearby center for ADRs reporting
were low 27.3 and 7.5%, respectively. However, respondents’ score on components of
attitude of ADRs reporting is generally encouraging. On comparative basis, no statistical
significance exists between pharmacists and nurses.
Conclusion: The study showed that attitude of respondents towards ADRs reporting is
good. However, there is a need for targeted health education intervention among these
cadres of health‑care professionals, especially on aspects of awareness of reporting
protocol and reporting center.
Keywords
health programmes: Pharmacovigilance an essential tool.
The Uppsala Monitoring; 2006. www.who.int/medicines/
areas/quality_safety_efficacy/pharmacovigilance_B.pdf
[Last accessed on 2015 Apr 15].
2. Pirmohamed M, James S, Meakin S, Green C, Scott AK,
Walley TJ, et al. Adverse drug reactions as cause of admission
to hospital: Prospective analysis of 18 820 patients. BMJ
2004;329:15‑9.
3. Ye X, Fu Z, Wang H, Du W, Wang R, Sun Y, et al. Acomputerized
system for signal detection in spontaneous reporting system of
Shanghai China. Pharmacoepidemiol Drug Saf 2009;18:154‑8.
4. Brvar M, Fokter N, Bunc M, Mozina M. The frequency of
adverse drug reaction related admissions according to method
of detection, admission urgency and medical department
specialty. BMC Clin Pharmacol 2009;9:8.
5. Oshikoya KA, Chukwura H, Njokanma OF, Senbanjo IO, Ojo I.
Incidence and cost estimate of treating pediatric adverse drug
reactions in Lagos, Nigeria. Sao Paulo Med J 2011;129:153‑64.
6. Inman WH. Attitudes to adverse drug reaction reporting. Br
J Clin Pharmacol 1996;41:434‑5.
7. Hajebi G, Mortazavi SA, Salamzadeh J, Zian A. A survey
of knowledge, attitude and practice of nurses towards
pharamacovigilance in Taleqani hospital. Iran J Pharm Res
2010;9:199‑206.
8. Desai CK, Iyer G, Panchal J, Shah S, Dikshit RK. An evaluation
of knowledge, attitude, and practice of adverse drug reaction
reporting among prescribers at a tertiary care hospital.
Perspect Clin Res 2011;2:129‑36.
9. Smith CC, Bennett PM, Pearce HM, Harrison PI, Reynolds DJ,
Aronson JK, et al. Adverse drug reactions in a hospital general
medical unit meriting notification to the Committee on Safety
of Medicines. Br J Clin Pharmacol 1996;42:423‑9
)