Document Type : Original Article
Authors
- . Kasturi Mukherjee 1
- . Anjan Das 2
- . Sandip Roy Basunia 2
- . Soumyadip Dutta 3
- . Parthajit Mandal 4
- . Anindya Mukherjee 5
1 Department of Biochemistry, Medical College, Kolkata, West Bengal, India
2 Department of Anaesthesiology, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India
3 Department of Orthopedics, R.G Kar Medical College, Kolkata, West Bengal, India
4 Department of G and O, College of Medicine and Sagore Dutta Hospital, Kolkata, West Bengal, India
5 Department of Anaesthesiology, N.R.S Medical College and Hospital, Kolkata, West Bengal, India
Abstract
Objective: Different additives have been used to prolong brachial plexus block. We
evaluated the effect of adding magnesium sulfate to ropivacaine for supraclavicular brachial
plexus blockade. The primary endpoints were the onset and duration of sensory and motor
block and duration of analgesia.
Methods: One hundred patients(25–55 years) posted for elective forearm and hand surgeries
under supraclavicular brachial plexus block were divided into two equal groups (Groups RM
and RN) in a randomized, double‑blind fashion. In group RM (n = 50), 30 ml 0.5% ropivacaine
plus 150 mg (in 1 ml 0.9% saline) magnesium sulfate and in group RN (n = 50), 30 ml 0.5%
ropivacaine plus 1 ml normal saline were administered in supraclavicular block. Sensory
and motor block onset times and block durations, time to first analgesic use, total analgesic
need, postoperative visual analog scale (VAS), hemodynamic variables, and side effects were
recorded for each patient.
Findings: Though with similar demographic profile and block (sensory and motor) onset
time, the sensory and motor block duration and time to first analgesic use were significantly
longer and the total need for rescue analgesics was lower in group RM (P = 0.026) than
group RN. Postoperative VAS values at 24 h were significantly lower in group RM (P = 0.045).
Intraoperative hemodynamics was comparable among two groups and no appreciable side
effect was noted throughout the study period.
Conclusion: It can be concluded from this study that adding magnesium sulfate to
supraclavicular brachial plexus block may increase the sensory and motor block duration
and time to first analgesic use, and decrease total analgesic needs, with no side effects.
Keywords
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