Document Type : Original Article
Authors
Department of Pediatrics, Child Growth and Development Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
Abstract
Objective: It is well known that a brief exposure to 100% oxygen for only a few minutes
could be toxic for a preterm infant. The effectiveness of neonatal resuscitation was compared
with low concentration oxygen (30%) and high concentration oxygen (HOG) (100%).
Methods: Thirty-two preterm neonates were born in Isfahan Shahid Beheshti hospital
with gestational age of 29-34 weeks who required resuscitation were randomized into
two groups. The resuscitation was begun with 30% O2 in low concentration oxygen group
(LOG). The infants were examined every 60-90 seconds and if their HR was less than 100,
10% was added to the previous FIO2
(fraction of inspired oxygen) until the HR increased
to 100 and SO2
(saturation of oxygen) increased to 85%. In HOG resuscitation begun with
100% O2
and every 60-90 seconds, FIO2
was decreased 10 – 15% until the HR reached to
100 and SO2
reached to 85%.
Findings: The FIO2
in LOG was increased stepwise to 45% and in HOG was reduced to
42.1% to reach stable oxygen saturation more than 85% at the fifth minute in both groups.
At the first and third minutes after birth and there was no significant differences between
groups in heart rate and after 1,2,4 and 5 minutes after the birth there was also no significant
differences in SO2
between groups, regardless of the initial FIO2
.
Conclusion: We can safely initiate resuscitation of preterm infants with a low FIO2
(approximately 30%) oxygen and then oxygen should be adjusted with the neonates needs.
Keywords
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